Unit 4 · Cell Communication & Cell Cycle
Lesson 30 of 65

4.6 Cell Cycle

01Interphase

Most of a cell's life is interphase: G₁ (growth, normal work), S (DNA replication — each chromosome becomes two sister chromatids), G₂ (prepare for division). Cells that stop dividing enter G₀ (most neurons, muscle cells).

02Mitosis and cytokinesis

Prophase: chromosomes condense, spindle forms. Metaphase: chromosomes line up at the middle. Anaphase: sister chromatids separate to opposite poles. Telophase: nuclei re-form. Cytokinesis splits the cytoplasm — cleavage furrow in animals, cell plate in plants.

Result: two genetically identical diploid daughter cells. Mitosis is for growth, repair and asexual reproduction.

03Notebook box

DNA content per cell: G₁ = 1x → after S = 2x → after cytokinesis = 1x each. Chromosome NUMBER stays the same.

Worked example: A human cell in G₂ has how many chromosomes and chromatids? → 46 chromosomes, 92 chromatids.

Key takeaways
  • ✦Interphase = G₁, S, G₂; DNA copied in S.
  • ✦PMAT then cytokinesis.
  • ✦Mitosis makes identical daughter cells.
Watch outChromosome number does NOT double in S phase — DNA amount doubles, but sister chromatids still count as one chromosome.
Quick check

Did it stick?

1.DNA replication occurs during…

2.Sister chromatids separate during…

3.Nerve cells that no longer divide are in…