Unit 2 · Cell Structure & Function
Lesson 8 of 65

2.1 Cell Structure: Subcellular Components

01Two kinds of cells

Prokaryotes (bacteria, archaea) have no nucleus and no membrane-bound organelles. Their DNA sits in a region called the nucleoid. Eukaryotes (plants, animals, fungi, protists) wrap their DNA in a nucleus and divide the cell into membrane-bound compartments.

Both kinds share four things: a plasma membrane, cytoplasm, ribosomes, and DNA. If an exam asks what ALL cells have, those are the answer.

02The parts and what they do

Ribosomes — made of rRNA and protein, they build proteins. Free ribosomes make proteins used in the cytosol; ribosomes bound to the rough ER make proteins that will be secreted or placed in membranes.

Endoplasmic reticulum — the rough ER (studded with ribosomes) folds and modifies proteins; the smooth ER makes lipids, detoxifies drugs, and stores calcium.

Golgi complex — receives vesicles from the ER, modifies proteins (for example, adding sugar tags), sorts them and ships them out in new vesicles.

Mitochondria — the site of aerobic respiration, making most of the cell's ATP. Chloroplasts (plants/algae) carry out photosynthesis.

Lysosomes — sacs of digestive enzymes that break down worn-out parts and engulfed material. Vacuoles store water and materials; the plant central vacuole keeps the cell firm (turgor).

03Notebook box

Protein secretion pathway: nucleus (mRNA) → rough ER ribosome → ER lumen (folding) → transport vesicle → Golgi (modify, sort) → secretory vesicle → plasma membrane (exocytosis).

Worked example: A cell makes huge amounts of digestive enzymes to export. Which organelles will be unusually abundant? → Rough ER and Golgi, because secreted proteins are built on bound ribosomes and packaged by the Golgi.

Key takeaways
  • ✦All cells: membrane, cytoplasm, ribosomes, DNA.
  • ✦Secreted proteins travel rough ER → Golgi → vesicle → out.
  • ✦Organelle number matches cell job (muscle = many mitochondria).
Watch outRibosomes are NOT membrane-bound organelles — that's why prokaryotes can have them.
Quick check

Did it stick?

1.Which structure is found in BOTH prokaryotic and eukaryotic cells?

2.A protein destined to be secreted is first made on…

3.Liver cells detoxify alcohol and drugs. Which organelle is expanded in them?